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化学phd能懂药理吗。antihistamines本身就有止吐的作用。比如meclizine治motion sickness。在没有brand name decligis之前,很多都用B6或者antihistamines,包括doxylamine,diphenhydramine等等, 治疗morning sickness的。更何况在clinical trials里面绝大多数病人都要吃到三次(4片)decligis才有效果。一天要吃三次,还能算“缓释”吗?
kate0000 发表于 2/14/2018 10:25:53 PM

谢谢你的科普。你这么懂药理,那我很奇怪为什么你居然不知道VB6能止吐? 而且diclegis的确是叫“ delayed-release combination pill ”呀。
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990370/In April 2013, the US Food and Drug Administration (FDA) approved doxylamine succinate 10 mg and pyridoxine hydrochloride (a vitamin B6analog) 10 mg as a delayed-release combination pill called Diclegis for the treatment of NVP.
最后编辑Cath226 最后编辑于 2018-02-14 23:17:01
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